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Seaport Therapeutics, Inc.
Seaport Therapeutics, Inc. operates as a clinical-stage biopharmaceutical company advancing the development of novel neuropsychiatric medicines. The company develops therapeutic candidates for conditions such as depression and anxiety disorders using its proprietary Glyph technology platform.
The Glyph platform is designed to enable oral bioavailability, bypass first-pass metabolism, and reduce liver enzyme elevations or hepatotoxicity and other side effects.
Ticker, listing venue and issuer profile
Pricing terms and IPO milestones
Change from offer price to today
Real-time price; headline % change is vs first trade (listing price)
USD · NASDAQ:NASDAQ:SPTX
Key valuation ratios and metrics
Balance sheet strength and liquidity
Margins and return on capital
Street consensus and price targets
Volatility versus the market
Historical financial performance
Market history and supplemental quote data
| Date | Open | High | Low | Close | Adj. Close | Change | Volume |
|---|---|---|---|---|---|---|---|
| 2026-05-29 | $18.61 | $18.68 | $17.84 | $18.19 | $18.19 | -0.42 | 112,600 |
| 2026-05-28 | $17.88 | $19.30 | $17.88 | $18.80 | $18.80 | +0.92 | 316,700 |
| 2026-05-27 | $18.00 | $18.24 | $17.80 | $18.05 | $18.05 | +0.05 | 118,300 |
| 2026-05-26 | $17.72 | $18.25 | $17.32 | $18.01 | $18.01 | +0.29 | 181,100 |
| 2026-05-22 | $17.19 | $17.69 | $16.53 | $17.50 | $17.50 | +0.31 | 214,600 |
| 2026-05-21 | $16.00 | $17.52 | $15.67 | $17.19 | $17.19 | +1.19 | 209,900 |
| 2026-05-20 | $16.34 | $16.76 | $15.52 | $15.78 | $15.78 | -0.56 | 266,100 |
| 2026-05-19 | $15.67 | $16.26 | $15.01 | $15.66 | $15.66 | -0.01 | 158,900 |
| 2026-05-18 | $16.85 | $16.85 | $15.00 | $15.74 | $15.74 | -1.11 | 421,800 |
| 2026-05-15 | $16.77 | $17.23 | $16.19 | $16.81 | $16.81 | +0.04 | 611,600 |
| 2026-05-14 | $16.50 | $17.36 | $16.10 | $16.94 | $16.94 | +0.44 | 380,300 |
| 2026-05-13 | $16.10 | $16.70 | $15.57 | $16.50 | $16.50 | +0.40 | 431,700 |
| 2026-05-12 | $15.39 | $16.05 | $15.30 | $15.95 | $15.95 | +0.56 | 155,000 |
| 2026-05-11 | $16.00 | $16.44 | $14.94 | $15.25 | $15.25 | -0.75 | 399,500 |
| 2026-05-08 | $15.75 | $16.24 | $15.44 | $16.05 | $16.05 | +0.30 | 304,100 |
| 2026-05-07 | $16.05 | $16.08 | $14.85 | $15.50 | $15.50 | -0.55 | 429,700 |
| 2026-05-06 | $16.01 | $16.46 | $15.35 | $16.00 | $16.00 | -0.01 | 498,600 |
| 2026-05-05 | $17.35 | $17.86 | $15.21 | $16.00 | $16.00 | -1.35 | 892,700 |
| 2026-05-04 | $19.17 | $19.17 | $16.90 | $17.00 | $17.00 | -2.17 | 910,700 |
| 2026-05-01 | $21.00 | $23.00 | $19.50 | $19.84 | $19.84 | -1.16 | 4,697,700 |
Official documents from SEC EDGAR
| Form | Filing Date | Document |
|---|---|---|
| SCHEDULE 13D | May 11, 2026 | Filing |
| SCHEDULE 13G | May 11, 2026 | Filing |
| SCHEDULE 13D | May 6, 2026 | Filing |
| 8-K | May 4, 2026 | Current Report |
| S-8 | May 4, 2026 | Securities to be offered to employees in employee benefit plans |
| 424B4 | May 1, 2026 | Prospectus |
| EFFECT | Apr 30, 2026 | Notice of Effectiveness |
| S-1MEF | Apr 30, 2026 | Registration adding securities to prior Form S-1 registration |
| CERT | Apr 30, 2026 | Certification by an exchange approving securities for listing |
| 8-A12B | Apr 28, 2026 | Registration of securities |
Contact and headquarters details
Key executives and officers
Daphne Zohar
Chief Executive Officer and Director
Michael C. Chen, Ph.D.
Chief Scientific Officer
Lana Gladstein, J.D.
General Counsel
Antony Loebel, M.D.
Chief Medical Officer
Lauren A. White
Chief Financial Officer
Steven M. Paul, M.D.
Director and Board Chair
Eric Elenko, Ph.D.
Director
James I. Healy, M.D., Ph.D.
Director
Robert J. Hombach
Director
Robert Nelsen
Director

USD · NASDAQ:SPTX
Issue Size
$254.88M
Price Range
$16.00 - $18.00
Shares
53.03M o/s · 14.16M offered
Listing Price
$21.00
Listing date
May 01, 2026
Sector
Healthcare